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Spanish to English: The use of Rauwolfia serpentina in antihypertensive therapy General field: Science
Source text - Spanish Se ha estimado que, durante la década de los 40 del pasado siglo, más de un millón de personas afectas de hipertensión fueron tratadas en la India con comprimidos elaborados con polvo de raíz de Rauwolfia o con extractos líquidos de este material. Aunque algunos químicos y farmacólogos occidentales, como M. Raymond-Hamet (París), E.I. van Itallie y J. Steenhauer (Leiden) o Joseph Koepfli (Baltimore), se interesaron por esta planta (18), su actividad terapéutica no trascendió a la medicina occidental hasta 1949, fecha en la que Rustom Jal Vakil (Fig. 6A) publicó, en el British Heart Journal, los resultados de su experiencia clínica de 10 años en el manejo de pacientes hipertensos con Rauwolfia en el King Edward Memorial de Bombay (25). Los resultados del ensayo clínico controlado de Vakil, sobre una muestra de 50 pacientes colaboradores diagnosticados de hipertensión esencial y tratados con tres comprimidos diarios de “Serpina” (extracto de raíces secas de Rauwolfia serpentina fabricado por Himalaya Drug Company en Bombay), confirmaron un efecto hipotensor evidente al cabo de la primera semana (25).
Translation - English It has been estimated that during the 1940s, more than one million people suffering from hypertension were treated in India with tablets made with powdered root or liquid extracts of Rauwolfia. Although some Western chemists and pharmacologists, like M. Raymond-Hamet (Paris), E.I. van Itallie and J. Steenhauer (Leiden) or Joseph Koepfli (Baltimore), became interested in this plant (18), its therapeutic activity did not reach Western medicine until 1949, when Rustom Jal Vakil (Fig. 6A) published, in the British Heart Journal, the results of his 10 years of clinical experience in managing hypertensive patients with Rauwolfia at King Edward Memorial in Mumbai (25). The results of Vakil’s controlled clinical trial, in a sample of 50 patients diagnosed with essential hypertension and treated with three tablets of "Serpina" daily (extract of dried roots of Rauwolfia serpentina manufactured by the Himalaya Drug Company in Mumbai), confirmed a hypotensive effect evident at the end of the first week (25).
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Bachelor's degree - University of Michigan
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Years of experience: 16. Registered at ProZ.com: May 2008.
I am a US expat living in Peru. I have a bachelor's degree in Latin American and Caribbean Studies and a master's degree in Social Work, both from the University of Michigan. I am fluent in Spanish and my native language is English.