Glossary entry (derived from question below)
French term or phrase:
de son déclenchement
English translation:
at which it is released
Added to glossary by
Kelly Harrison
Jul 15, 2012 23:14
12 yrs ago
3 viewers *
French term
de son déclenchement
French to English
Medical
Medical (general)
dehydration / thirst
Concernant le système arginine-vasopressine, il a été démontré que les œstrogènes pouvaient augmenter l’expression de vasopressine par l’intermédiaire de leurs récepteurs béta au niveau des noyaux supra-optiques et paraventriculaires. Il en résulte une rétention hydrique permettant de diminuer l’ingestion d’eau (43). Cette augmentation du taux de vasopressine serait due à un abaissement du seuil osmotique ***de son déclenchement*** (44). Ce phénomène pourrait également intervenir dans la sensation de « non soif » comme c’est le cas chez la personne âgée. Ainsi la déshydratation relative de nos rats expliquerait leur « préférence » accrue au sel lors du test gustatif. Nos résultats suggèrent donc que le BPA puisse avoir un effet sur la sensation de soif via un effet de type oestrogéno-mimétique d’origine centrale.
My brain is slowing down and I can't work this out at all... thanks for your help!
My brain is slowing down and I can't work this out at all... thanks for your help!
Proposed translations
(English)
| 5 +3 | for its release |
Michael Barnett
|
| 5 | from it's release; on release |
Alison Billington
|
| 4 | at which it is triggered |
Ryan_Fr2Eng (X)
|
Proposed translations
+3
37 mins
Selected
for its release
The vasopressin is stored in the posterior pituitary and released into the bloodstream by various signals.
From Wikipedia article on vasopressin:
It is derived from a preprohormone precursor that is synthesized in the hypothalamus and stored in vesicles at the posterior pituitary. Most of it is stored in the posterior pituitary to be released into the bloodstream; however, some AVP is also released directly into the brain, where it plays an important role in social behavior and bonding.
Translate the sentence as: This rise in the level of vasopressin would be due to the lowering of the osmotic threshold for its release.
(Normally vasopressin reduces blood osmolarity by causing water retention, thereby diluting the blood. A lowering of the osmotic threshold for release means that the vasopressin is signaled to release sooner (ie at a lower osmolarity.) It follows logically that the blood vasopressin level would then be higher, the blood more dilute, and, if thirst triggered by blood osmolarity, then there would be a reduction of thirst.
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Note added at 41 mins (2012-07-15 23:55:39 GMT)
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BTW, in this context, taux refers to the vasopressin blood level, not its rate of release.
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Note added at 14 hrs (2012-07-16 14:11:54 GMT)
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Your suggestion works well for me Kelly! :-)
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Note added at 17 hrs (2012-07-16 16:23:41 GMT)
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@Kelly re is vs would be.
There is a subtle difference in meaning.
The source text was "serait due" which means essentially that the author supposes that the increase of serotonin was due the the osmolarity threshold change. He is not willing to declare it as a fact.
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Note added at 17 hrs (2012-07-16 16:24:52 GMT)
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Sorry, I mean vasopressin, not serotonin.
From Wikipedia article on vasopressin:
It is derived from a preprohormone precursor that is synthesized in the hypothalamus and stored in vesicles at the posterior pituitary. Most of it is stored in the posterior pituitary to be released into the bloodstream; however, some AVP is also released directly into the brain, where it plays an important role in social behavior and bonding.
Translate the sentence as: This rise in the level of vasopressin would be due to the lowering of the osmotic threshold for its release.
(Normally vasopressin reduces blood osmolarity by causing water retention, thereby diluting the blood. A lowering of the osmotic threshold for release means that the vasopressin is signaled to release sooner (ie at a lower osmolarity.) It follows logically that the blood vasopressin level would then be higher, the blood more dilute, and, if thirst triggered by blood osmolarity, then there would be a reduction of thirst.
--------------------------------------------------
Note added at 41 mins (2012-07-15 23:55:39 GMT)
--------------------------------------------------
BTW, in this context, taux refers to the vasopressin blood level, not its rate of release.
--------------------------------------------------
Note added at 14 hrs (2012-07-16 14:11:54 GMT)
--------------------------------------------------
Your suggestion works well for me Kelly! :-)
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Note added at 17 hrs (2012-07-16 16:23:41 GMT)
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@Kelly re is vs would be.
There is a subtle difference in meaning.
The source text was "serait due" which means essentially that the author supposes that the increase of serotonin was due the the osmolarity threshold change. He is not willing to declare it as a fact.
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Note added at 17 hrs (2012-07-16 16:24:52 GMT)
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Sorry, I mean vasopressin, not serotonin.
Note from asker:
| Thanks Michael, would this not be more accurate though, in your opinion: "The rise in the level of vasopressin would be due to the lowering of the osmotic threshold at which it is released." ? |
| Thank you :o) I used "is" instead of "would be" though. A very nice evening to all! |
| Oh mince! bon, je vais donc apporter cette petite modification à l'auteur. Merci encore! |
Peer comment(s):
| agree |
Gurudutt Kamath
: http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd...
1 hr
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Thanks Gurudutt! Good reference.
|
|
| agree |
Bertrand Leduc
7 hrs
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|
Thanks Bernard!
|
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| agree |
Drmanu49
7 hrs
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Thanks Manu!
|
4 KudoZ points awarded for this answer.
Comment: "Thank you very much Michael!"
15 mins
at which it is triggered
You could say "at which it occurs", but I have chosen the above because it represents an action that is triggered by another action i.e. the lowering of a threshold.
Example sentence:
This increased rate of vasopressin is due to a lowering of the osmotic threshold at which it is triggered.
Note from asker:
| Ah oui c'est tellement évident maintenant! Merci beaucoup! |
7 hrs
Alison Billington
United Kingdom
United Kingdom
Native in English
Specializes in field
United Kingdom
Translator of French to English
Native in: English (Variant: British)
Works in: French to English, English, French
Related KudoZ points
:
4
from it's release; on release
The context is a flood of biochemical. This is released and triggers something else. Note 'de' meaning from the time it is released or on it's release.
Note from asker:
| Thank you, but I would say de means "of" instead of "from"! |
Discussion
So, case closed :oD