Endoxan : 600 mg iv covered Uromitexan

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Note added at 22 mins (2022-02-01 11:52:49 GMT)
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Endoxan: 600 mg IV covered by Urometexan. ( Urometexan is given to cover Endoxan, probably in order to avoid some adverse reactions or for other reason. In this situations we usually say that medication X is covered by medication Y)

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Note added at 29 mins (2022-02-01 11:59:38 GMT)
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Explanation:
Endoxan : 600 mg iv covered by Uromitexan ( and NOT Endoxan : 600 mg iv covered Uromitexan, as I wrote by mistake in the explanation, I can not change.)

It should be clear to medical people why the two drugs are administered together, but something like "cotreatment", "combined with", etc. might result in non-experts thinking both contribute actively to remedying the problem, where in fact Endoxan can damage the bladder lining and Uromitexan counters that side effect to at least some extent.

The French have gone to the trouble of indicating the protective nature of the administration. This should be repeated in English, I feel. "Under the protection of" is short and sweet and would probably be clear to the professional.

"in conjunction with Uromitexan to counter adverse side effects" is exact, I think, but lengthy.

Note that the square brackets are mine.

ENDOXAN [...] Il est recommandé d'associer l'administration [d'Endoxan] d'Uromitexan (Mesna) à partir de 600 mg/m2/j et/ou d'assurer une hydratation suffisante (absorption ou perfusion) pendant ou immédiatement après la prise du traitement pour réaliser une diurèse forcée et prévenir ainsi le risque de toxicité des voies urinaires.
https://base-donnees-publique.medicaments.gouv.fr/affichageD...

Endoxan is a cyclophosphamide

"COMPOSITION DU MÉDICAMENT ENDOXAN
p cp p fl p fl
Cyclophosphamide 50 mg 500 mg 1 000 mg"
https://www.vidal.fr/medicaments/gammes/endoxan-21176.html

"ENDOXAN (cyclophosphamide)"
https://www.has-sante.fr/jcms/c_2627627/fr/endoxan-cyclophos...

"Uromitexan
(mesna)
DIN (Drug Identification Number)
02241411 UROMITEXAN 100MG/ML INJECTION"
https://www.medbroadcast.com/drug/getdrug/uromitexan

"The chemotherapy drugs ifosfamide and cyclophosphamide [ENDOXAN] can sometimes irritate the lining of the bladder. This can cause bleeding from the bladder and may show up as blood in your urine (pee). This is called haematuria. Mesna [UROMETIXAN] helps protect your bladder to prevent irritation and bleeding."
https://www.macmillan.org.uk/cancer-information-and-support/...

"Administrer l’ENDOXAN® (500 à 1500 mg selon les cas) dilué dans 250 ml de Sérum Salé 0.9%, en dérivation avec l’UROMITEXAN®, 200 mg dilué dans 100 ml de Sérum Salé 0.9%. La perfusion doit passer en 1 heure environ."
http://www.rhone-alpes-sep.org/wp-content/uploads/2013/03/EN...

"Indications UROMITEXAN
Prévention de la toxicité urinaire des oxazaphosphorines (CYCLOPHOSPHAMIDE à fortes doses: ≥ 600 mg /m2/J, ifosfamide quelle que soit la dose)."
https://www.doctissimo.fr/medicament-UROMITEXAN.htm

French term (edited): sous couvert d\'Uromitexan

"Protection", "uroprotection" or "bladder protection" may work as well.

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Name: Mesna

Alternate Names:
D 7093
Mesna rescue
Mesnex
Mesnex uroprotection
Mesnum
Mistabron
Mitexan
Mucofluid
Sodium 2-mercaptoethanolsulfonate
UCB 3983
Uromitexan

Abbreviations: None

Category: Ancillary Agent

Subcategory: None

NSC Number: 113891

Primary Site: None

Histology: None

Remarks: A prophylactic detoxifying agent used to inhibit hemorrhagic cystitis caused by ifosfamide. FDA approved for bladder protection when using cyclophosphamide (prevents bladder toxicity).
https://seer.cancer.gov/seertools/seerrx/rx/53c44b01102c1290...