liz askew Sep 15, 2012:

http://bioprocessintl.com/journal/2010/April/Understanding-t...

Definitions: Peptides are short polymers formed from the linking of (usually ≤100) amino acids. They comprise some of the most basic components of human biological processes, including enzymes and hormones. The link between one amino acid residue and the next is known as a peptide bond or an amide bond — formed when a carboxyl group reacts with an amine group of an adjacent residue — giving this class of chemicals its name.
Proteins, by contrast, are longer chains of (>100) amino acids similarly linked by peptide bonds. They play a critical role in biochemical reactions within cells. Proteins are ubiquitous in cellular chemistry and structure and are crucial for carrying out most biological functions of living organisms. Scientists follow various conventions to determine the distinction between peptides and proteins. Generally speaking, however, peptide chains are short and proteins are long.

Filippe Vasconcellos de Freitas Guimarães Sep 15, 2012:

By the way I will contact the creator of the Wikipedia article (a physician and acquaintance of mine) and let him know of this discussion. Perhaps the article itself is due for a name change; Wikipedia guidelines generally recommend that "the scientific or recognised medical name that is most commonly used in recent, high-quality, English-language medical sources" be used as the title of any medicine-related article [ http://en.wikipedia.org/wiki/Wikipedia:MEDMOS ]

Filippe Vasconcellos de Freitas Guimarães Sep 15, 2012:

Some notes Both are "correct". The terms are interchangeable although a case could be made for a semantic difference. All proteins are peptides though not all peptides are proteins.
Now, for the case and the semantic difference:
When the anti-CCP test and the rationale behind it were first developed, the researchers used synthetic (lab-manufactured) oligopeptides (peptides consisting of only a few amino acids bound in sequence) instead of natural proteins. Hence, "cyclic citrullinated peptide". The original report is here (very interesting, although it makes for rather dense reading :) http://onlinelibrary.wiley.com/doi/10.1002/1529-0131(200001)...

A cursory PubMed search shows that more recent articles have used "protein/peptide", for instance: http://www.clinchem.org/content/53/3/498.full

"Protein" is correct because the test antibodies, as used in vivo, bind to natural proteins that have undergone the process of citrullination.

As for Wikipedia—as a longstanding administrator, my advice is (a) never use it as your only source though (b) it is indeed very, very reliable for such uses (i.e. checking the names of things).

[Edit: formatting

ganaa444 Sep 5, 2012:

Why is it in the English-Mongolian pair when you seem to be trying to find out the meaning of the abbreviation in English? If you need the translation in Mongolian, we are ready to help you.

liz askew Sep 4, 2012:

Hi, I think you should post the entire sentence with your phrase included.
FWIW, Wikipedia is not a reliable academic source.