Sep 4, 2020 00:54
4 yrs ago
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inglés term

co-crystals

GBK inglés al español Medicina Medicina (general)
Definition from Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.
Example sentences:
In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one (Indian J Pharm Sci.)
In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. (Dove Press)
As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. (Regulatory Focus™)
Proposed translations (español)
5 +3 cocristales
Change log

Aug 22, 2020 01:05: changed "Kudoz queue" from "In queue" to "Public"

Sep 4, 2020 00:55: changed "Stage" from "Preparation" to "Submission"

Sep 7, 2020 01:55: changed "Stage" from "Submission" to "Completion"

Proposed translations

+3
1 hora
Selected

cocristales

Múltiples referencias en español
Definition from Scientific Journal:
Los cocristales farmacéuticos son sólidos cristalinos constituidos por un IFA y un formador, los cuales se encuentran en la misma celda cristalina.
Example sentences:
Los cocristales farmacéuticos surgen como una posibilidad para mejorar las propiedades biofarmacéuticas y farmacotécnicas de un IFA (Ingrediente Farmacéutico Activo). (Scientific Journal)
Existen técnicas que forman con el principio activo sales, solvatos, polimorfos y, además, existen otras técnicas más novedosas como dispersiones sólidas amorfas y cocristales. (Scientific Thesis)
Una reciente guía de la FDA pone mayor atención en los cocristales como una herramienta en la formulación de formas farmacéuticas sólidas. (Scientific Journal)
Peer comment(s):

agree Alberto Gómez Herrera : Perfect translation for it, widely used in Chemistry, Medicine and other sciences to describe co-crystallised (simultaneously crystallised) substances. Good job.
6 horas
agree Monica Garcia : This is the correct translation of the term.
9 horas
agree Robert Copeland
22 horas
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4 KudoZ points awarded for this answer.
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