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    • anglais
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        • Term
          • disease-modifying anti-rheumatic drug (DMARD)
        • Additional fields of expertise
        • Definition(s)
          • Disease-modifying antirheumatic drugs (DMARDs) are a class of drugs indicated for the treatment of inflammatory arthritides including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). They can also be used to in the treatment of other disorders including connective tissue disease such as systemic sclerosis (SSc), systemic lupus erythematosus (SLE), and Sjogren syndrome (SS), as well as in treatment of inflammatory myositis, vasculitis, uveitis, inflammatory bowel disease, and some types of cancers. National Center for Biotechnology Info.
        • Example sentence(s)
          • Hydroxychloroquine has been available since 1955 as an antimalarial drug. I have at least 6 patients at the pharmacy who have used hydroxychloroquine to manage their rheumatoid arthritis, lupus, and Crohn disease. If you were sitting in my pharmacology class, I’d tell you that it is an antimalarial used as a disease-modifying antirheumatic drug (DMARD). I would tell you it is a cheap drug with good efficacy for some and also that it is 1 of 2 DMARDs that are safe to use in patients with liver failure. You would also learn that it may cause deposition of the drug in the melanin layer of the cones in the retina, underscoring the need for annual eye exams. - MJH Life Sciences by
          • DMARDs Not Linked to Poor Outcomes in SARS-CoV-2 RA Patients - Rheumatology Network by
          • The analysis of performance measures for rheumatoid arthritis (RA) care have allowed to identify gaps in care that include suboptimal use of disease-modifying anti-rheumatic drugs (DMARDs), according to a study published in Arthritis Care & Research. - Rheumatology Advisor by
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    • italien
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        • Term
          • Farmaco antireumatico modificante la malattia (DMARD)
        • Additional fields of expertise
        • Definition(s)
          • I farmaci antireumatici modificanti la malattia ovvero Disease-modifying antirheumatic drugs (DMARDs) possiedono proprietà antinfiammatorie pensate per essere mediate, in alcuni casi, dall'inibizione del rilascio o dell'attività delle citochine Essi, a differenza di analgesici ed antinfiammatori non steroidei, non sono semplicemente sintomatici ma agiscono sui meccanismi che sono alla base delle malattie infiammatorie croniche. Sono utilizzati nel trattamento dell'artrite reumatoide e dell'artrite idiopatica giovanile Alcuni sono di beneficio nella spondilite anchilosante e nell'artrite psoriasica. Molti DMARD possiedono anche altre proprietà terapeutiche e sono utilizzati in condizioni non reumatiche. Medicina Interna - by Luigi Argentino
        • Example sentence(s)
          • La rivoluzione dei farmaci biologici che ha avuto luogo nell'ultimo ventennio ha trasformato il panorama terapeutico dell'artrite reumatoide. Dall'introduzione del primo farmaco antireumatico modificante la malattia (DMARD) biologico, un gran numero di farmaci biologici ha fatto il suo ingresso nella pratica clinica, sfruttando diversi meccanismi terapeutici. Gli attuali farmaci biologici funzionano in base a quattro meccanismi diversi: inibizione del TNF, inibizione dell'interleuchina-6, blocco della costimolazione dei linfociti T e deplezione dei linfociti B. È stato ampiamente dimostrato che l'efficacia dei farmaci biologici è superiore rispetto a quella dei DMARD convenzionali; i farmaci biologici sono inoltre ben tollerati. Nel complesso sono efficaci nel ridurre i sintomi, rallentare il danno articolare e la progressione della malattia, migliorando la funzione fisica e la qualità della vita dei pazienti1,2. - Lilly by Luigi Argentino
          • Tofacitinib in associazione con MTX è indicato per il trattamento dell’artrite psoriasica attiva (PsA) in pazienti adulti che hanno risposto in modo inadeguato o sono intolleranti ad una precedente terapia con un farmaco antireumatico modificante la malattia (DMARD) - EMA (Agenzia Regolatoria europea) by Luigi Argentino
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    • néerlandais
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        • Term
          • Ziekteverloop beïnvloedende geneesmiddelen tegen reuma
        • Additional fields of expertise
        • Definition(s)
          • Disease-modifying antirheumatic drugs ("ziekteverloop beïnvloedende geneesmiddelen tegen reuma") of DMARD's vormen een groep geneesmiddelen die de activiteit van ontstekingen in de gewrichten vermindert. De middelen worden gegeven met als doelstelling het zo veel mogelijk voorkomen van gewrichtsbeschadiging zoals die bij reumatoïde artritis veel voorkomen. nl.wikipedia.org - by Stieneke Hulshof
        • Example sentence(s)
          • Sulfasalazine is een middel dat ontstekingen in de gewrichten onderdrukt bij een aantal vormen van reuma. Het is sinds 1944 op de markt. Dit medicijn behoort tot de zogenaamde DMARDs. Deze letters staan voor Disease-Modifying AntiRheumatic Drugs wat ‘ziekteverloop beïnvloedende geneesmiddelen tegen reuma’ betekent. - Bewegenzonderpijn.com by Stieneke Hulshof
          • Artsen schrijven vaak medicijnen voor bij artritis om de symptomen en de voortschrijding van de ziekte in bedwang te houden. Er zijn verschillende categorieën van medicatie bij artritis: NSAIDs (niet-steroïde anti-inflammatoire drugs), analgetica (pijnstillers), DMARDs (ziekteverloop beïnvloedende geneesmiddelen tegen reuma), biologische middelen, en corticosteroïden. - Artroseblog.nl by Stieneke Hulshof
          • psoriatische artritis (ontsteking van de gewrichten die geassocieerd wordt met psoriasis) wanneer ziekteverloop beïnvloedende geneesmiddelen tegen reuma (‘disease-modifying anti-rheumatic drugs’ – DMARD’s) niet goed genoeg werken; - Ema.Europa.eu by Stieneke Hulshof
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    • bulgare
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        • Term
          • антиревматично лекарство, променящо заболяването
        • Additional fields of expertise
        • Definition(s)
          • Антиревматичните лекарства, променящи заболяването (DMARDs), са клас лекарства, показани за лечение на възпалителни артрити, включително ревматоиден артрит (RA), псориатичен артрит (PsA) и анкилозиращ спондилит (AS). National Center for Biotechnology Info - by Andrei Vrabtchev
        • Example sentence(s)
          • Какво е DMARD? DMARD или антиревматично лекарство, променящо заболяването, е всичко, което се използва за лечение на ревматоиден артрит (RA), който може да забави или предотврати увреждане на ставите, за разлика от просто облекчаване на болката или възпалението. DMARDs могат "да променят фундаментално процеса на това как болестта атакува тялото", казва Ерик Л. Матесън, д.м., председател по ревматология в клиниката Mayo, в Рочестър, Мин. - https://bg.healthcnn.com/20-dmards-used- by Andrei Vrabtchev
          • За лечение на ревматоиден артрит пенициламинът е известен като антиревматично лекарство, променящо заболяването (DMARD). Това лекарство помага за намаляване на болката / болката / подуването в ставите. - bul.len-med.com by Andrei Vrabtchev
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