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Japanese Translator specialize in Pharmacy, Medicine, Science and Travelling (Pharm.D., JLPT N2, ENG CEFR B1)
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Specializes in:
Science (general)
Medical: Pharmaceuticals
Medical (general)
Medical: Health Care
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English to Thai: Efficacy and safety of sitafloxacin in patients with urinary tract infections (Takuyuki Matsumoto et al., 2012) General field: Medical Detailed field: Medical: Pharmaceuticals
Source text - English Abstract
Sitafloxacin (STFX, Gracevit 50mg, fine granules 10%), a new quinolone antibacterial agent, was approved in January 2008, and the use-results survey was carried out over the 2 years between December 2008 and November 2010.
We studied the efficacy and safety of STFX in 1,452 patients with urinary tract infections (cystitis, pyelonephritis, urethritis).
The total efficacy rate for urinary tract infections was 91.4% (1,235/1,351 patients). Efficacy rates, classified by the type of infection, were: uncomplicated cystitis 95.9% (466/486 patients), complicated cystitis 87.2% (511/586 patients), uncomplicated pyelonephritis 96.1% (49/51 patients), complicated pyelonephritis 93.5% (145/155 patients), and urethritis 87.7% (64/73 patients).
Efficacy rates were 86.0% (49/57 patients) for non-responders to cephems and 77.4% (48/62 patients) for non-responders to quinolones. The eradication rate of indicated strains was 90.5% (545/602 strains).
The eradication rates of major causative bacteria were; Escherichia coli 92.7% (294/317 isolates), Enterococcus faecalis 86.0% (43/50 isolates), Pseudomonas aeruginosa 66.7% (16/24 isolates), Klebsiella pneumoniae 95.2% (20/21 isolates), and Chlamydia trachomatis 88.9% (8/9 isolates).
The incidence of adverse drug reactions (ADRs) was 2.71% (37/1,365 cases). Major ADRs were diarrhoea (0.88%, 12 cases) and hepatic function disorders (0.51%, 7 cases). A serious ADR (hepatic function abnormality) was observed in 1 case, and the hepatic function in this patient returned to normal after treatment with STFX was discontinued.
In conclusion, these results suggest that STFX is a useful antibacterial agent with an efficacy rate of 91.4% against urinary tract infections, with a minimum efficacy rate of 87.2% (against complicated cystitis), and has no serious problems in its safety profile.
English to Thai: โรคฝีดาษ (Smallpox) General field: Medical Detailed field: Medical (general)
Source text - English First Aid Topic: Smallpox
1. Definition
What is Smallpox?
Smallpox is an acute, contagious, and sometimes fatal disease caused by the variola virus (an orthopoxvirus), and marked by fever and a distinctive progressive skin rash. In 1980, the disease was declared eradicated following worldwide vaccination programs.
What are some signs and symptoms of Smallpox?
The symptoms of smallpox begin with high fever, head and body aches, and sometimes vomiting. A rash follows that spreads and progresses to raised bumps and pus-filled blisters that crust, scab, and fall off after about three weeks, leaving a pitted scar.
2. Take action
What should I do?
There is no proven treatment for smallpox, but research to evaluate new antiviral agents is ongoing. Early results from laboratory studies suggest that the drug cidofovir may fight against the smallpox virus; currently, studies with animals are being done to better understand the drug’s ability to treat smallpox disease (the use of cidofovir to treat smallpox or smallpox reactions should be evaluated and monitored by experts at NIH and CDC). Patients with smallpox can benefit from supportive therapy (e.g., intravenous fluids, medicine to control fever or pain) and antibiotics for any secondary bacterial infections that may occur.
When should I seek medical care?
If you think you might have smallpox, contact your doctor immediately. For most people, the smallpox vaccine is safe & effective. Most people experience normal, typically mild reactions to the vaccine, which indicate that it is beginning to work. Some people may experience reactions that may require medical attention…
3. Prevention
How I should avoid?
To avoid:
The smallpox vaccine helps the body develop immunity to smallpox.
Some people should not be vaccinated or should wait.
A person who has ever had a life-threatening allergic reaction after a previous dose of any tetanus or diphtheria containing vaccine, OR has a severe allergy to any part of this vaccine, should not get Td vaccine. Tell the person giving the vaccine about any severe allergies.
Talk to your doctor if you:
have seizures or another nervous system problem,
had severe pain or swelling after any vaccine containing diphtheria or tetanus,
ever had a condition called Guillain Barré Syndrome (GBS),
aren't feeling well on the day the shot is scheduled.
(Reference: Centers for Disease Control and Prevention, CDC)
- Academic Conference "From Evidence-Based Medicines to Clinical Pharmacy Practice Research: NCD and Infections in Pediatrics" organized by Mahasarakham University, Thailand. (2020)
- Short Course Training Certification "Adverse Drug Reaction Monitoring (Basic Course)" organized by The Association of Hospital Pharmacy, Thailand. (2019)
- Academic Conference "Pharmacy Review and Update Series 2018: Pharmacotherapy of Pain and Palliative Care" organized by Mahidol University, Thailand. (2018)
- Professional Internship in acute care, ambulatory care at Udonthani hospital, Thailand. (2016)
- Short-term Student Exchange Program "Saga University Summer Program 2014 (SUSP2014) : Creating Innovation for Sustainability in Young Leaders" at Saga University, Japan. (2014)
- Certificate of Attendance "The Promotion of Academic Olympiad and Development of Science Education Foundation under the patronage of Her Royal Highness Princess Galyani Vadhana Krom Luang Naradhiwas Rajanagarindra: Physics (2nd camp)" at Suranaree University of Technology, Thailand. (2010)
- Participated "Thai Science Camp 2009" organized by the The Science Society of Thailand Under the Patronage of His Majesty the King with the National Science Museum, Thailand. (2009)
- Certificate of Achievement "Document Translation from English into Thai (Intermediate Level)": the 30-hour legal and medical document translation training program. organized by Southeast Asian Association of Professional Translators and Interpreters (SEAProTI). (2022)
Expertise