Glossary entry (derived from question below)
Japanese term or phrase:
ALT優位の肝障害
English translation:
ALT-dominant liver disorder
Added to glossary by
Deborah Edwards
Aug 22 23:57
19 days ago
11 viewers *
Japanese term
Australia
15 years working in Medical Translation
Native in: English 
Works in: Japanese to English
ALT優位の肝障害
Japanese to English
Medical
Medical (general)
Patient discharge summary
Hi everyone,
I am translating a patient referral document, and having trouble translating the above term. The patient is experiencing unexplained abdominal pain, and has hepatitis...
TIA!
I am translating a patient referral document, and having trouble translating the above term. The patient is experiencing unexplained abdominal pain, and has hepatitis...
TIA!
Proposed translations
(English)
| 3 +2 | ALT-dominant liver disorder |
Robert Edison
|
| 4 | Liver disorder with predominantly raised ALT |
biofilter3
|
| 4 -1 | Liver damage with significantly elevated ALT |
Hiroaki Masuda
|
Proposed translations
+2
3 hrs
Selected
ALT-dominant liver disorder
This doesn't seem to be a particularly common phrasing, but it does exist in published literature.
https://lipidworld.biomedcentral.com/articles/10.1186/1476-5...
"Damage to the liver typically results in a leak of AST and ALT into the bloodstream [20]. The AST/ALT ratio is usually 1 in NAFLD, it suggests an advanced fibrotic stage of disease. In a recent large survey of 12,808 men, ALT-dominant liver disorders were related to obesity, lack of physical exercise, and hyperlipidemia, whereas AST-dominant liver disorders were related to alcohol consumption and diabetes mellitus [21]."
https://lipidworld.biomedcentral.com/articles/10.1186/1476-5...
"Damage to the liver typically results in a leak of AST and ALT into the bloodstream [20]. The AST/ALT ratio is usually 1 in NAFLD, it suggests an advanced fibrotic stage of disease. In a recent large survey of 12,808 men, ALT-dominant liver disorders were related to obesity, lack of physical exercise, and hyperlipidemia, whereas AST-dominant liver disorders were related to alcohol consumption and diabetes mellitus [21]."
4 KudoZ points awarded for this answer.
Comment: "Thanks!"
-1
37 mins
Hiroaki Masuda
United States
United States
Native in Japanese
Specializes in field
United States
Related KudoZ points
:
4
Liver damage with significantly elevated ALT
I think 優位 is a typo and should read 有意.
So, this passage should read "ALTが有意に高い肝障害."
So, this passage should read "ALTが有意に高い肝障害."
Peer comment(s):
| disagree |
Yuka Kinoshita, MD, PhD
: I suppose it refers to the AST/ALT ratio. The translation would be "liver damage with an AST/ALT ratio < 1."
2 hrs
|
|
I think you are right. Please discard my proposed phrase.
|
3 days 21 hrs
biofilter3
United States
United States
Native in Japanese
Works in field
United States
JPNENG Med/Pharmaceutical translation
Native in: Japanese
Works in: English to Japanese, Japanese to English
Liver disorder with predominantly raised ALT
NIH and NHS (England) use the word of "predominantly raised ALT".
Example sentence:
About 31.3% of our patients developed liver test abnormalities, which were predominantly raised ALT.
Predominantly Raised ALT This guideline applies to adults over 18 years.
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