This question was closed without grading. Reason: Errant question
May 30, 2021 09:28
3 yrs ago
18 viewers *
Italian term
T3 solfato sodico
Italian to English
Medical
Medical: Pharmaceuticals
No context here. It's just from a list of pharmaceutical ingredients. Solfato sodico (or sulfato sodico) is obviously sodium sulfate, but I can't quite figure out where the T3 fits in. I get quite a few hits for T3 sulfate and even more for T3 sodium. Only one hit (from a Korean patent) for "T3 sodium sulfate", two questionable hits for "T3 sodium sulphate", none for "T3 sulphate sodium" six somewhat better hits for "T3 sulfate sodium", etc. Is this substance really that rare?
One of the articles from the search makes reference to "the thyroid hormone analogue O-[3-iodo-4-(sulfooxy)phenyl]-3,5-diiodo-l-tyrosine sodium salt (T3-sulfate, 1)" which gives us a clue as to what the T3 stands for, but the final solution remains out of my grasp. Any biochemists or pharmacists out there?
One of the articles from the search makes reference to "the thyroid hormone analogue O-[3-iodo-4-(sulfooxy)phenyl]-3,5-diiodo-l-tyrosine sodium salt (T3-sulfate, 1)" which gives us a clue as to what the T3 stands for, but the final solution remains out of my grasp. Any biochemists or pharmacists out there?
Reference comments
20 mins
Reference:
good start if not solution
https://www.clinicaltrialsregister.eu/ctr-search/trial/2011-...
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Note added at 2 hrs (2021-05-30 11:51:27 GMT)
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https://www.rxlist.com/cytomel-drug.htm
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Note added at 2 hrs (2021-05-30 11:52:47 GMT)
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... but wait for Luigi!
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Note added at 2 hrs (2021-05-30 11:54:15 GMT)
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see section on combined treatement
https://www.endocrinologiaoggi.it/2014/10/terapia-con-levoti...
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Note added at 2 hrs (2021-05-30 11:51:27 GMT)
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https://www.rxlist.com/cytomel-drug.htm
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Note added at 2 hrs (2021-05-30 11:52:47 GMT)
--------------------------------------------------
... but wait for Luigi!
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Note added at 2 hrs (2021-05-30 11:54:15 GMT)
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see section on combined treatement
https://www.endocrinologiaoggi.it/2014/10/terapia-con-levoti...
Note from asker:
Thanks Judy, I'll check it out. This will be a good resource for future projects as well! |
8 hrs
Reference:
Appena letto il titolo ho pensato all'ormone tiroideo. Il T3, molto noto in ambito farmaceutico anche per abusi legati al doping, è un farmaco a base di liotironina, ormone prodotto normalmente dalla tiroide e noto anche come triiodiotiroinina. In commercio, si presenta soprattutto come sale sodico. Per quanto riguarda il solfato, non mi risultano prodotti in commercio. Risulta tuttavia coniugato a ad un gruppo solfato nel processo di coniugazione del metabolismo epatico.
https://docplayer.it/39517835-Tiroide-unita-funzionali-folli...
https://docplayer.it/39517835-Tiroide-unita-funzionali-folli...
Discussion
Process Development and Scale-up of T3-Sulfate, A New ...https://www.researchgate.net › ... › Scale Up
An efficient and scalable preparation of the thyroid hormone analogue O-[3-iodo-4-(sulfooxy)phenyl]-3,5-diiodo-l-tyrosine sodium salt (T3-sulfate, 1) is reported.
EU Clinical Trials Registerhttps://www.clinicaltrialsregister.eu › ctr-search › trial
Farmacocinetica di T3 solfato (T3S)-sale sodico in volontari sani dopo somministrazione orale di una singola dose pari a 40-60-80 mcg. Studio clinico in singolo ...