Glossary entry

French term or phrase:

chimio aplasiante

English translation:

cytotoxic chemotherapy

Added to glossary by Jason Willis-Lee
Sep 28, 2005 10:05
18 yrs ago
4 viewers *
French term

aplasiante

French to English Other Medical: Health Care oncology: CT and RT
Health care research Q&As. Oncologists asked to fill in a questionnaire on their clinical habits....appears in the following context. TIA, Jason.

chimio aplasiante et radiotherapie sur un terrain general altere
Proposed translations (English)
4 +2 cytotoxic chemotherapy
5 +1 aplasia-inducing
3 aplasing
Change log

Sep 28, 2005 10:07: Anabel Martínez changed "Language pair" from "Spanish to English" to "French to English"

Proposed translations

+2
23 mins
Selected

cytotoxic chemotherapy

My first thought was aplasia-inducing chemotherapy, but the few references to this in English made me wonder. Certainly, in some French texts, "chimiothérapie aplasiante" refers specifically to the induction of bone marrow aplasia, for example, in preparation for a BM transplant. But otherwise it seems to be a general term for what we would call in English, cytotoxic chemotherapy.

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Note added at 7 hrs 21 mins (2005-09-28 17:26:38 GMT)
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In relation to bone marrow transplants, "high-dose chemotherapy".

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Note added at 22 hrs 34 mins (2005-09-29 08:40:06 GMT)
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In fact only 11 articles with "aplasia-inducing" turn up with a Google search. Three of these are by the same authors (Horn et al). About half are translations from other languages (French or German).
Peer comment(s):

agree Rachel Fell
1 min
thanks Rachel :-)
agree Emérentienne : I found this bilingual site where aplasiante actually is translated by aplasia inducing. Sorry, can't post the URL
6 mins
thanks, but only 15 g-hits for "aplasia-inducing" and not many native English articles got my alarm bell ringing :-)
disagree Georges Tocco : i think you were right with aplasia-inducing chemotherapy
5 hrs
maybe, but one has to make a distinction between literal translations, which are not wrong per se, and expressions that are actually used by English speakers :-)
agree Michael Lotz
1 day 2 hrs
thanks Michael!
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4 KudoZ points awarded for this answer. Comment: "Thanks Sue...."
23 mins

aplasing

An open phase I study assessing the feasibility of the triple ... - [ Traduire cette page ]
... previous antitumor treatment for at least 4 weeks (6 weeks in the case of
aplasing chemotherapy such as nitrosourea, mitomycin C and carboplatin). ...
annonc.oxfordjournals.org/cgi/content/full/14/3/481 - Pages similaires
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+1
5 hrs

aplasia-inducing

aplasia-inducing chemotherapy
see:
Histiocytofibromes multiples éruptifs.
Alors que l’histiocytofibrome est banal, les HCF multiples sont rares. On les a décrits dans des situations de déficit immunitaire comme les collagénoses et maladies auto-immunes, l’infection par le VIH ou la corticothérapie générale. C’est ici le second cas rapporté en association à une leucémie myéloïde chronique. Dans les mois suivant une CHIMIOTHERAPIE APLASIANTE par le busulfan sont apparus 13 HCF. La dépression de l’immunité cellulaire était manifeste puisque le patient a fait à la même période une pneumopathie et une candidose, et qu’il avait une lymphopénie globale, des intradermoréactions négative à la tuberculine et à la candidine et un taux abaissé d’anticorps circulants contre les antigènes de groupes sanguins. Après la récupération médullaire, les HCF ont régressé progressivement en deux mois et aucune nouvelle lésion n’est plus apparue.

Multiple eruptive dermatofibromas.
While dermatofibroma is common, multiple dermatofibromas (MDFs) are rare. They have been described in situations of immune deficiency such as collagenosis and self-immune diseases, HIV-induced infection or systemic corticotherapy. This case report is the second to report association with chronic myelogenous leukemia. 13 MDFs appeared during the months that followed APLASIA-INDUCING CHEMOTHERAPY using busulfan. Depression in cellular immunity was obvious as the patient simultaneously developed pneumopathy and candidosis, as well as presented global lymphopenia, intradermoreactions that did not respond to tuberculin and candidin, and a decreased level of circulating antibodies against blood group antigens. After medullary recovery, MDFs progressively receded two months later without the appearance of new lesions.

Peer comment(s):

agree sktrans
8 hrs
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