Glossary entry (derived from question below)
English term or phrase:
prior chemotherapy lines in the metastatic setting
Russian translation:
линии (курсы) химиотерапии, предшествовавшие стадии появления метастазов
Added to glossary by
Stanislav Korobov
Mar 29, 2009 22:40
15 yrs ago
13 viewers *
English term
prior chemotherapy lines in the metastatic setting
English to Russian
Medical
Medical: Health Care
Помогите перевести данную фразу.
the patient has had no prior chemotherapy lines in the metastatic setting.
Спасибо!
the patient has had no prior chemotherapy lines in the metastatic setting.
Спасибо!
Proposed translations
(Russian)
Change log
Apr 4, 2009 15:25: Stanislav Korobov Created KOG entry
Proposed translations
+3
3 hrs
Selected
до появления метастазов пациент никаких линий (курсов) химиотерапии не получал
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Note added at 3 hrs (2009-03-30 02:35:15 GMT)
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"line" может здесь подразумевать то же самое "line", что и в словосочетаниях "first-line therapy" и "second-line therapy"...
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Note added at 3 hrs (2009-03-30 02:38:22 GMT)
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Table 1. Patient and disease characteristics
...
**Prior chemotherapy lines*
Median number/patients (range): 3(1-6)
...
http://annonc.oxfordjournals.org/cgi/reprint/7/10/1065
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Note added at 3 hrs (2009-03-30 02:39:50 GMT)
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Критерии для подгрупп включали группу рандомизации, время после завершения последней химиотерапии, **число предшествовавших линий химиотерапии**, проводившееся ранее лечение таксанами, препарат платины, запланированный для лечения, возраст и функциональный статус.
http://medi.ru/doc/0446059.htm
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Note added at 4 hrs (2009-03-30 02:42:48 GMT)
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...tamoxifen generally is used as **first-line therapy in this setting**...
http://www3.interscience.wiley.com/cgi-bin/fulltext/75504663...
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Note added at 4 hrs (2009-03-30 02:44:27 GMT)
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Patients were pre-treated with a median of **two (range 1-4) conventional chemotherapy lines before** high-dose cyclophosphamide ...
http://www.haematologica.org/cgi/reprint/86/7/706
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Note added at 4 hrs (2009-03-30 02:45:58 GMT)
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...previous chemotherapy lines 1: 12 pts (34%), 2: 10 pts (28%), greater than or equal to3: 10 pts (28%).
http://www.nature.com/bjc/journal/v89/n10/full/6601382a.html
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Note added at 4 hrs (2009-03-30 02:47:02 GMT)
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...three or more previous chemotherapy lines...
http://annonc.oxfordjournals.org/cgi/content/full/15/8/1222
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Note added at 4 hrs (2009-03-30 02:48:04 GMT)
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Patients with recurrent ovarian carcinoma, 6 months after treatment with a platinum-based regimen and with **no more than two previous chemotherapy lines**, were randomized to receive carboplatin...
http://annonc.oxfordjournals.org/cgi/content/full/16/5/749
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Note added at 4 hrs (2009-03-30 02:50:40 GMT)
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In the last decade the treatment of advanced-metastatic non-small cell lung cancer has substantially improved. If in the early 90s there was still concern about the real efficacy of chemotherapy over best suppotive care
alone in the advanced setting, constant developments in clinical research have demonstrated the survival advantage of active anti-cancer drugs **not only in the first-line setting, but, lately, even in patients with recurrent disease after failure of two previous chemotherapy lines**. ...
http://annonc.oxfordjournals.org/cgi/reprint/17/suppl_2/ii36
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Note added at 4 hrs (2009-03-30 02:52:19 GMT)
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The median time elapsed between the beginning of the **first chemotherapy line** for metastatic disease and chronoIFLO onset was 24 months...
http://theoncologist.alphamedpress.org/cgi/content/full/11/1...
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Note added at 4 hrs (2009-03-30 02:55:01 GMT)
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**** METASTATIC SETTING:
IN THE ADJUVANT SETTING, AS OPPOSED TO THE METASTATIC SETTING, PATIENTS DO NOT HAVE ROOTED TUMORS. HOWEVER, THEY MIGHT HAVE TUMORS CIRCULATING IN THEIR BLOOD STREAM...
http://www.colorectal-cancer.ca/en/news-and-resources/genent...
4 KudoZ points awarded for this answer.
Comment: "Спасибо!"
56 mins
к началу стадии метастазов пациент не получал химиотерапию посредством катетера
chemotherapy lines:
"IV chemotherapy: Cancer Research UK: CancerHelp UK
Oct 22, 2008 ... Doctors often use central lines for chemotherapy because drips can be temperamental. They can stop and start when you move your arm."...
www.cancerhelp.org.uk/help/default.asp?page=302 - 24k - http://old.consilium-medicum.com/media/consilium/05_07/556.s...
http://www.ntpo.com/patents_medicine/medicine_6/medicine_168...
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Note added at 1 hr (2009-03-30 00:20:45 GMT)
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MISPRINT:конечно же, капельница, а не катетер!
Лучше сформулировать так: "к моменту начала стадии метастазирования пациент не получал химиотерапию внутривенно"
"IV chemotherapy: Cancer Research UK: CancerHelp UK
Oct 22, 2008 ... Doctors often use central lines for chemotherapy because drips can be temperamental. They can stop and start when you move your arm."...
www.cancerhelp.org.uk/help/default.asp?page=302 - 24k - http://old.consilium-medicum.com/media/consilium/05_07/556.s...
http://www.ntpo.com/patents_medicine/medicine_6/medicine_168...
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Note added at 1 hr (2009-03-30 00:20:45 GMT)
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MISPRINT:конечно же, капельница, а не катетер!
Лучше сформулировать так: "к моменту начала стадии метастазирования пациент не получал химиотерапию внутривенно"
6 hrs
ранее не получал курс химиотерапии в область метастазирования
Все-таки надо бы спросить у медиков, что имеется в виду, setting здесь больше похоже на область поражения, нежели процесс образования местаст. Для образовния должен использоваться другой термин
9 hrs
пациент не получал химиотерапии по поводу метастазирующего заболевания
Т.е., ранее пациент получал химиотерапию, но не специфичную для метастазирующей опухоли (там другие схемы лечения)
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