Glossary entry (derived from question below)
English term or phrase:
gene silencing
Slovak translation:
potlačenie transkripcie génov
English term
gene silencing
Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. (biotech-info.net)
The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? (The Thomson Corporation)
In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. (ScienceDaily LLC)
4 +2 | potlačenie transkripcie génov | Dagmar Turčanová |
4 | tlmenie génov, tlmenie aktivity génov | Igor Liba |
Feb 9, 2010 13:01: changed "Kudoz queue" from "In queue" to "Public"
Feb 9, 2010 13:59: changed "Stage" from "Preparation" to "Submission"
Feb 12, 2010 15:08: changed "Stage" from "Submission" to "Selection"
Mar 11, 2010 15:54: changed "Stage" from "Selection" to "Completion"
Proposed translations
potlačenie transkripcie génov
Zahrňuje potlačenie transkripcie génov (gene silencing) v závislosti na bunkovej diferenciácií (Jihočeská univerzita)
tlmenie génov, tlmenie aktivity génov
Následne výskumy zázvorového extraktu postúpili do fázy zisťovania inhibície – tlmenia niekoľkých génov zúčastňujúcich sa zápalovej reakcie. (Nutraceutika)
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