Oct 31, 2019 14:50
4 yrs ago
2 viewers *
English term
CYP-isoenzyme specific probe substrate
English to Russian
Medical
Medical: Pharmaceuticals
CYP450 inhibition in HLM, and CYP450 induction in cryopreserved human hepatocytes Tesetaxel 0.025 to 10 µmol/L
Tesetaxel 0.025 to 10 µmol/L
For inhibition, appearance of CYP-isoenzyme specific probe substrate metabolites;
For induction, mRNA levels of CYP450 by RT-PCR and appearance of isoenzyme specific probe substrate metabolite by LC-MS/MS, cell viability
Tesetaxel 0.025 to 10 µmol/L
For inhibition, appearance of CYP-isoenzyme specific probe substrate metabolites;
For induction, mRNA levels of CYP450 by RT-PCR and appearance of isoenzyme specific probe substrate metabolite by LC-MS/MS, cell viability
Proposed translations
(Russian)
3 | см. |
Igor Andreev
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Proposed translations
37 mins
Selected
см.
isoenzyme specific probe substrate metabolite = метаболиты/продукты метаболизма изофермент-специфического тестового субстрата
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Note added at 38 mins (2019-10-31 15:28:59 GMT)
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здесь один метаболит
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Note added at 46 mins (2019-10-31 15:37:03 GMT)
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потерял еще цитохром Р450... Все вместе:
метаболит тестового изоформ-специфического субстрата цитохрома P450
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Note added at 38 mins (2019-10-31 15:28:59 GMT)
--------------------------------------------------
здесь один метаболит
--------------------------------------------------
Note added at 46 mins (2019-10-31 15:37:03 GMT)
--------------------------------------------------
потерял еще цитохром Р450... Все вместе:
метаболит тестового изоформ-специфического субстрата цитохрома P450
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Comment: "Спасибо!"
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