Dec 10, 2007 20:10
16 yrs ago
English term
derivatized with an adipic hydrazide spacer
English to Russian
Medical
Medical: Pharmaceuticals
immunology
Это процесс получения конъюгатной вакцины против Haemophilus influenzae типа b.
The Hib polysaccharide is produced from Haemophilus influenzae type b strain 760705. The polysaccharide is generated by fermentation and purified by a series of precipitation and ultrafiltration steps. The purified polysaccharide is activated with cyanogens bromide, and derivatized with an adipic hydrazide spacer and then covalently bound to carrier protein Tetanus Toxoid.
The Hib polysaccharide is produced from Haemophilus influenzae type b strain 760705. The polysaccharide is generated by fermentation and purified by a series of precipitation and ultrafiltration steps. The purified polysaccharide is activated with cyanogens bromide, and derivatized with an adipic hydrazide spacer and then covalently bound to carrier protein Tetanus Toxoid.
Proposed translations
(Russian)
3 | получают производное со спейсером, гидразидом адипиновой кислоты | Pavel Venediktov |
Proposed translations
54 mins
Selected
получают производное со спейсером, гидразидом адипиновой кислоты
Т.е. полисахарид присоединяют к белку токсоида через разделитель (или мостик), которым является гидразид адипиновой кислоты. Но спейсер стало уже почти русским словом.
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