This question was closed without grading. Reason: Other
Feb 14, 2021 18:17
3 yrs ago
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English term

biomarker positive stratum

English to Polish Medical Medical: Health Care protocol synopsis
If statistical significance is achieved in this biomarker positive stratum, then hierarchically a pooled analysis of the biomarker positive and biomarker negative strata would be conducted

Discussion

Frank Szmulowicz, Ph. D. Feb 15, 2021:
On the basis of
prior retrospective analyses of patients with recurrent glioblastoma treated with EGFR inhibitor therapy (29, 30),
patients with either intact PTEN or EGFRvIII expression were
stratified as biomarker-positive; those without PTEN and
EGFRvIII expression were stratified as biomarker-negative.

https://clincancerres.aacrjournals.org/content/clincanres/ea...
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