Glossary entry

English term or phrase:

flavopiridol

Chinese translation:

(一种抗癌新药,属黄酮类化合物)

Added to glossary by XiaoRan
Dec 4, 2004 13:59
19 yrs ago
English term

flavopiridol

English to Chinese Science Medical (general)
征求 flavopiridol 的翻译

Discussion

Non-ProZ.com Dec 5, 2004:
to Yueyin Sun ��Ȼ��ֲ������ȡ�Ļ�ͪ�໯����, ��ôӦ�ð�����ҩ��Ч�ɷֵ�������. �Ұ����Ϊ "�г�ľ��ͪ" �� "���г�ľ��ͪ" ��������? ������ҩ��Ч�ɷֵ���������Ȩ. (������һ�����: �ҵ����һ�νӴ�endostatin��ʱ��, ��ҩû�б���, ���Dz���, �����ٴβ��й���ϵ�ʱ��,��Ѿ�����Ϊ "��Ƥ����" ��, ���Һܿ��Ҷ�����������. ��ʵ�ҵ�ʱ��Ҳ�����������ֵ�).

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Non-ProZ.com Dec 5, 2004:
to Shang ���� flavin �ṹ http://www-biol.paisley.ac.uk/marco/Enzyme_Electrode/Chapter...
��� pyridol
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Non-ProZ.com Dec 4, 2004:
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Proposed translations

2 hrs
Selected

FYI

这是一种抗癌新药,恐怕还没有正式的中文译名。除非你得到有关机构的授权,否则即使译成了中文也未必得到公认。故建议不必为它伤脑筋,而保留原文名称。从以下网页上的结构式看,它属于黄酮类衍生物。

http://clltopics.org/Chemo/flavopiridol.htm

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Note added at 1 day 5 hrs 34 mins (2004-12-05 19:34:14 GMT)
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If I were you, I would translate it as \"细胞周期抑制剂flavopiridol\" so that the readers would know its function as well as the original name.
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4 KudoZ points awarded for this answer. Comment: "Thank you! But I don't think I should put 细胞周期抑制剂in the translation. Because most of 老外 don't know it's 细胞周期抑制剂 unless they read related articles as we do."
+1
20 mins

黄素吡多

...

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Note added at 44 mins (2004-12-04 14:43:31 GMT)
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根据手头的药学词典,flavo-翻译成黄素,-piridol翻译成吡多
Peer comment(s):

agree Chinoise
31 mins
thanks!
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1 hr

扶拉平渡

音译,just like 百服宁.
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8 hrs

抗癌新药

Flavopiridol是目前进入II期临床的治疗MCL的一种针对细胞周期设计的新药物。它是从印度植物中提炼的植物碱,植物的叶和根是印度应用的草药。美国第一个针对细胞周期进入临床试验的药物。Flavopiridol抑制蛋白激酶cyclin D1及cdk1—4,阻碍细胞从G1期进入S期,引起细胞周期阻滞。同时,它具有直接细胞毒性。因此, Flavopiridol对增殖期和静止期细胞均有作用。
象许多其他药物一样,Flavopiridol通过阻断对细胞分化至关重要的蛋白来发挥作用。自1998年以来,它已被用于肾癌、前列腺癌、结肠癌及其他癌症的临床试验。去年一种新型强效Flavopiridol已展露光芒:该Flavopiridol也可以阻断帮助DNA转录成为信使RNA(messenger RNA,mRNA)的蛋白,这是从基因到蛋白产生的第一步,使所有细胞赖以生存的一个过程。国家癌症研究所的癌症研究者Louis Staudt和他的同事很好奇flavopiridol对于B淋巴细胞的作用。

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Note added at 8 hrs 47 mins (2004-12-04 22:46:57 GMT)
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建议不要翻译,保留原文.
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