破盲

--------------------------------------------------
Note added at 4 hrs 27 mins (2004-10-14 05:32:19 GMT)
--------------------------------------------------

随机化和设盲

一旦受试者随机化，其操作过程须书面载明。在一项设盲和随机化的研究中，提供的是每个人治疗的密封编码，这应该由申办者和试验单位保存。中国医药资讯网 WWW.YY2000

对设盲的试验，试验方案必须述明允许破盲的条件和由谁破盲。也需要有一个系统在紧急情况下能获得个别受试者接受治疗的资料。这系统只允许获得一名受试者在一个时期的治疗时间表。若作破盲，必须在病例报告表上述明正当理由。

见：
http://www.yy2000.com/xinyaodongtai/gcppeixun/sjwszjyplcsygl...

--------------------------------------------------
Note added at 4 hrs 30 mins (2004-10-14 05:35:21 GMT)
--------------------------------------------------

Treatments were assigned by random permutation blocks (fixed block size=4, 1 to 3 complete blocks per center) according to chronological order of inclusion within each center. During double-blind phases, participants, investigators, and outcome assessors were blinded to the treatment assignments. Placebo and the 3 ivabradine doses were supplied in tablets of identical shape, appearance, and taste, in blister packs identified by the study phase number and patient random assignment number. At study onset, investigators received a set of randomization envelopes for secure storage enabling CODE-BREAKING in emergencies.
见：
http://circ.ahajournals.org/cgi/content/full/107/6/817

--------------------------------------------------
Note added at 4 hrs 33 mins (2004-10-14 05:38:22 GMT)
--------------------------------------------------

亦有称：揭盲

--------------------------------------------------
Note added at 7 hrs 6 mins (2004-10-14 08:10:58 GMT)
--------------------------------------------------

Perfectly fit in!
熟悉试验的（设盲）随机化和揭盲（或破盲）方法（或程序）。