Jun 30, 2020 11:48
4 yrs ago
18 viewers *
English term
mammary analgoue secretory cancer
English to Hungarian
Science
Medical: Pharmaceuticals
kontextus: ppt diasorban felsorolás, egy ritka típusú nyálmirigyrák, de vajon mi ez magyarul?
Proposed translations
(Hungarian)
3 +1 | az emlő szekretoros karcinómájával ekvivalens nyálmirigydaganat (MASC) | András Illyés |
Proposed translations
+1
7 hrs
az emlő szekretoros karcinómájával ekvivalens nyálmirigydaganat (MASC)
Nem találtam meg magyarul (ahogy itt látom, egy 2016 körül leírt új tumortípusról van szó), egy fiatalkori emlődaganattal ekvivalens:
Definition: Mammary analogue secretory carcinoma (MASC) is a low-grade malignant tumor of salivary glands resembling secretory breast carcinoma, including histopathologic and immunohistochemical features and t(12;15)(p13;q25) translocation with ETV6-NTRK3 gene fusion.
First description: MASC was first described and genetically defined by Alena Skálová et al. [1], who proposed the current term, and documented the similarity between the salivary and the secretory mammary carcinoma, also known as juvenile breast cancer.
It has been generally accepted that the salivary gland and the mammary tumor are completely equivalent to each other as shown reproducibly by a number of histopathologic, immunohistochemical, cytogenetic, and molecular genetic features.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978118/
MASC is characterized by morphologic and immunohistochemical features that strongly resemble a secretory carcinoma (SC) of the breast.
https://www.sciencedirect.com/science/article/pii/S221026121...
Definition: Mammary analogue secretory carcinoma (MASC) is a low-grade malignant tumor of salivary glands resembling secretory breast carcinoma, including histopathologic and immunohistochemical features and t(12;15)(p13;q25) translocation with ETV6-NTRK3 gene fusion.
First description: MASC was first described and genetically defined by Alena Skálová et al. [1], who proposed the current term, and documented the similarity between the salivary and the secretory mammary carcinoma, also known as juvenile breast cancer.
It has been generally accepted that the salivary gland and the mammary tumor are completely equivalent to each other as shown reproducibly by a number of histopathologic, immunohistochemical, cytogenetic, and molecular genetic features.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978118/
MASC is characterized by morphologic and immunohistochemical features that strongly resemble a secretory carcinoma (SC) of the breast.
https://www.sciencedirect.com/science/article/pii/S221026121...
Discussion
MASC (***synonym: secretory carcinoma***) are characterized by a specific rearangement of the ETV6 gene locus. Here, we present a series of 3 MASC cases ...