May 17, 2020 00:55
4 yrs ago
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English term
vitamin k-dependent plasma glycoprotein
COVID-19
GBK
English to Chinese
Science
Medical (general)
Definition from
Science Direct:
Vitamin K–dependent proteins, synthesized in the liver, play a central role in blood coagulation through either procoagulant or anticoagulant mechanisms. The vitamin K–dependent protein family includes the zymogen procoagulant factors VII, IX, X, and prothrombin, and the anticoagulants protein C, protein S, and protein Z
Example sentences:
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. (National Center for Biotechnology Info.)
Protein Z is a vitamin K-dependent glycoprotein isolated and characterized from human and bovine plasma. A cDNA coding for human protein Z has been obtained by the isolation of phage clones from a liver cDNA library and in vitro amplification of two other liver libraries. (Research Gate)
Four proteins active in blood coagulation have long been known to require vitamin K for their proper biosynthesis: factors II, VII, IX, and X. This paper describes the purification of a hitherto unrecognized vitamin K-dependent glycoprotein from bovine plasma. The biosynthesis of this protein is interfered with by the vitamin K antagonist Dicoumarol. (The JBC)
Proposed translations
(Chinese)
5 +1 | 维生素K-依赖性血浆糖蛋白 | CHEN-Ling |
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