English to Russian Law/Patents Medical: Pharmaceuticals технология получения лекарственных средств

описывают модель для определения проницаемости

In the experimental setup for the determination of the permeation, shown in figure 1, 90 ml of the acceptor medium 13, which is covered underneath the skin sample that should be examined with a metal grille 12, is tempered to 35 °C and transferred continuously through pump 1 with 1000 ml/h. The permeation chamber 5, which is filled with the acceptor medium 13 has a volume of 50 ml, the compensation vessel 3 for the sampling and the tubes 4 has a total volume of 40 ml. The lumen can be filled with various, skin-physiological solutions. Authoritative for the choice of the acceptor medium is the solubility of the active ingredient and its verification.

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