Glossary entry (derived from question below)
English term or phrase:
bioavailability
Serbian translation:
biološka raspoloživost
English term
bioavailability
Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential. (Merck & Co., Inc. )
The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. (Informa plc )
Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. (US National Institutes of Health)
5 +2 | biološka raspoloživost | Mira Stepanovic |
4 | bioraspoloživost | Katarina Delic |
Nov 17, 2009 16:25: changed "Kudoz queue" from "In queue" to "Public"
Nov 17, 2009 16:59: changed "Stage" from "Preparation" to "Submission"
Nov 20, 2009 17:54: changed "Stage" from "Submission" to "Completion"
Proposed translations
biološka raspoloživost
S i m p o z i j u m ‚‚Ispitivanje biološke raspoloživosti i biološke ekvivalentnosti lekova - regulatorni i praktični aspekti” (Agenc. za lekove i med. sredstva Srbije)
Sublingvalnom i rektalnom primenom postiže se bolja biološka raspoloživost, nego posle per os primene. (Farmaceutski fakultet, Beograd)
Koncentracije leka niže od očekivanih najčešće su rezultat slabe biološke raspoloživosti leka, njegove brže eliminacije u odnosu na očekivanu, povećanog volumena distribucije ili nepostignutog stanja ravnoteže (1,2,5). Alternativno praćenje imunosupresivnih (Medicinski fakultet, Niš)
bioraspoloživost
Po definiciji, bioraspoloživost leka primenjenog intravenozno je 100%. (Wikipedia)
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