Glossary entry

English term or phrase:

bioavailability

Romanian translation:

biodisponibilitate

Nov 17, 2009 16:55
14 yrs ago
English term

bioavailability

GBK English to Romanian Medical Medical: Pharmaceuticals
a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc.
Example sentences:
Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential. (Merck & Co., Inc. )
The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. (Informa plc )
Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. (US National Institutes of Health)
Proposed translations (Romanian)
4 +8 biodisponibilitate
Change log

Nov 17, 2009 16:15: changed "Kudoz queue" from "In queue" to "Public"

Nov 17, 2009 16:55: changed "Stage" from "Preparation" to "Submission"

Nov 20, 2009 16:59: changed "Stage" from "Submission" to "Completion"

Proposed translations

+8
6 mins
Selected

biodisponibilitate

Definition from innovatics:
Biodisponibilitatea reprezinta gradul de absorbtie a substantei active dintr-un produs (medicament /supliment nutritiv/nutraceutic, etc.), respectiv cat % din substanta activa administrata ajunge la organul tinta. Biodisponibilitatea este direct proportionala cu eficienta produsului administrat.
Example sentences:
Biodisponibilitatea este raportul dintre cantitatea de substanţă activă precum şi viteza cu carea aceasta este este cedată, absorbită în organism, ajunge la locul de acţiune şi işi manifestă efectul biologic.Cunoaşterea biodisponibilităţii unui medicament poate duce la modificarea parametrilor acestuia: mod de administrare, durată etc (wikipedia)
Peer comment(s):

agree George C.
15 mins
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agree Victorița Ionela Duță
36 mins
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agree M&T (X)
56 mins
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agree Monica Contolencu
14 hrs
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agree Ciprian Bojan
20 hrs
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agree Julia Bogdan Rollo (X)
1 day 3 hrs
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agree Cosmin Roman-Tarciniu
2 days 12 hrs
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agree Maria Diaconu
2 days 22 hrs
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