English to Russian Tech/Engineering Medical: Pharmaceuticals ���������

The blender was loaded top-to-bottom to produce an axially symmetrical initial condition. However, because the blender is not symmetric in a top-to-bottom sense, the initial conditions produced a gradient in concentration from the middle of the blender outward (see Figure 12). As sampling in situ was limited to the middle of the blender, this axial gradient was overlooked and the mixture may have appeared to be better blended than it really was. After discharge, the mixture was more thoroughly sampled which results in this apparent separation during discharge that was actually the result of better sampling techniques. During discharge, the axial variability was transformed into radial variability. Although in this case (a nonsegregating mixture) the quality of the mixture was expected to improve upon discharge, the apparent decrease in quality was solely a function of improved sampling of the mixture.