Glossary entry

English term or phrase:

tampered dosage form

English answer:

dosage form has been manipulated by mechanical, thermal, and/or chemical means

Added to glossary by Oso (X)
Sep 16, 2005 06:28
19 yrs ago
6 viewers *
English term

tampered

English Medical Medical: Pharmaceuticals
administration of a tampered dosage form to a patient population
Change log

Sep 16, 2005 16:26: Oso (X) changed "Field" from "Law/Patents" to "Medical"

Responses

+6
5 mins
Selected

dosage form has been manipulated (more info. below)

"...The term "tampered dosage form" is defined for purposes of the present invention to mean that *****the dosage form has been manipulated by mechanical, thermal, and/or chemical means which changes the physical properties of the dosage***** for, e.g., to liberate the opioid agonist forimmediate release if it is in sustained release form, or to make the opioid agonist available for inappropriate use such as administration by an alternate route, e.g., parenterally. The tampering can be, e.g., by means of crushing, shearing, grinding, chewing, dissolution in a solvent, heating, (e.g., greater than about 45.degree. C.), or any combination thereof. ..."

http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=...

Good luck from Oso ¶:^)
Peer comment(s):

agree Anne Grimes : sorry Oso, didn't see you already answered!
3 mins
Don't worry, anne. Surely we were writing at the same time ¶:^) Thanks! ¶:^)
agree Rajan Chopra
1 hr
Thanks, langclinic ¶:^)
agree Janet Ratziu
1 hr
Thanks, Janet ¶:^)
agree Jeannie Graham
2 hrs
Thanks, kalimeh ¶:^)
agree Alfa Trans (X)
2 days 53 mins
Thank you, Marju ¶:^)
agree Jörgen Slet
6 days
Thanks, Jörgen ¶:^)
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4 KudoZ points awarded for this answer. Comment: "Thanks :)"
6 mins

when the dosage is tampered, such as by crushing a tablet

when the dosage is tampered, it is changed, for example when crushed for ease in swallowing.
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