English to Russian Medical Medical: Pharmaceuticals clinical study

Most importantly, the absolute estimated effect of the d,l-leucovorin exceeded the minimal clinically important difference, suggesting that the effect was not only statistically significant but also clinically meaningful.

https://www.sciencedirect.com/science/article/pii/S107190912...

The minimal important difference (MID) or minimal clinically important difference (MCID) is the smallest change in a treatment outcome that an individual patient would identify as important and which would indicate a change in the patient's management

https://en.wikipedia.org/wiki/Minimal_important_difference