Sep 24, 2005 23:50
19 yrs ago
English term

bisphosphonate

English to Chinese Medical Chemistry; Chem Sci/Eng
A composite end point may be appropriate when the drug’s benefit is multifaceted. The end-point components should be related and generally of similar clinical importance. Pamidronate was the first bisphosphonate drug approved to decrease morbidity of skeletal metastases; it was initially approved for myeloma and, subsequently, for breast cancer.
“二磷酸酯“or“二膦酸盐"?

Discussion

Jianming Sun (asker) Sep 27, 2005:
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Jianming Sun (asker) Sep 26, 2005:
Anyway thank you!

Proposed translations

+4
37 mins
Selected

biphosphonate drugs = biphosponates = 双膦酸盐类药物

骨质疏松症药物治疗进展(二) - [ Translate this page ]
近3 0年来,双膦酸盐类(bisphosphonates)药物已发展成为最有效的骨吸收抑制剂。由于它
能减少各种原因引起的骨吸收,因此被用来 ... (4)一项为期2年的随机双盲安慰剂对照研究
显示,241例男性原发性骨质疏松症患者应用阿仑膦酸钠(一日10mg)治疗后,骨密度较 ...
www.medboo.com/cmsweb/webportal/W14301/A10012535.html - 20k - Cached - Similar pages

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Note added at 39 mins (2005-09-25 00:30:28 GMT)
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sorry, 好像 should be bisphosphonates not biphosphonates, my mistake.

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Note added at 42 mins (2005-09-25 00:33:38 GMT)
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Yes, bisphosphonates (a family of drugs):

Bisphosphonates are a family of drugs used to prevent and treat osteoporosis. There are three bisphosphonates currently approved for use in ...
www.osteoporosis.ca/english/About Osteoporosis/ Drug%20Treatments/Bisphosphonates/default.asp?s=1 - 27k - Cached - Similar pages


Bisphosphonates : CancerBACUPThis section is about bisphosphanates which are used help protect bones against some of the effects of cancer particularly myeloma, breast cancer and ...
www.cancerbacup.org.uk/Treatments/ Supportivetherapies/Bisphosphonates - 26k - 22 Sep 2005 - Cached - Similar pages

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Note added at 9 hrs 27 mins (2005-09-25 09:18:49 GMT)
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第38章抗骨质疏松的药物 - [ Translate this page ]
抑制骨吸收的药物包括双膦酸盐(bisphosphonates)、降钙素(calcitonin) 、雌
激素(estrogen)、依普黄酮(iprioavone)等;刺激骨 ... 氯屈膦酸二钠 Clodronate disodium.
Clodronate disodium为第二代双膦酸盐类药物,又名骨膦,洛屈,氯甲双磷酸二钠等。 ...
jpkc.gdmc.edu.cn/yl/charper%2038.htm - 248k - Cached - Similar pages



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Note added at 6 days (2005-10-01 09:45:10 GMT)
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I think this is a pharmaceuticals question rather than a chemistry one, so the naming conventions are a little different from straight chemistry -> you get families of commercial chemicals and drugs (the same happens with agricultural chemicals such as herbicides and insecticides).

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Note added at 6 days (2005-10-01 09:46:40 GMT)
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http://64.233.187.104/search?q=cache:5fhXcWd9ulsJ:www.medter...
Peer comment(s):

agree Han Li : 磷酸盐白喉类毒素diphtheria phosphonate toxoid;磷酸酯phosphonate ester
22 mins
Thanks
agree Shang
2 hrs
agree Ritchest
8 hrs
agree ysun : 双膦酸盐
2 days 6 hrs
Thanks
Something went wrong...
3 KudoZ points awarded for this answer. Comment: "Thank you both!"
2 days 1 hr

二碳磷酸盐化合物

请看Longman Dictionary of Contemporary English的解释
phosphate
1
one of the various forms of a salt of phosphorus, often used in industry
2
[usually plural] a substance containing a phosphate used for making plants grow better
phosphate大部分时间也写作phosphonate
你可能只局限于查phosphonate了,
所以biphosphonate drugs = 双膦酸盐类药物
磷酸酯应该为phosphonate ester

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Note added at 2 days 1 hr 52 mins (2005-09-27 01:43:38 GMT)
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bisphosphonate etidronic acid
依替膦酸二膦酸盐


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Note added at 2 days 1 hr 55 mins (2005-09-27 01:46:14 GMT)
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二碳磷酸盐化合物
应该把“碳”字去掉,不知怎么修改了
Something went wrong...
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