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grobfleckige Fibrose
an der Haut adaptierter Patch

Glossary entry

German term or phrase:

klein- bis großtropfige Leberzellverfettung

English translation:

micro- and macrovesicular steatosis

Added to glossary by @caduceus (X)
Sep 8, 2007 04:04
16 yrs ago
8 viewers *
German term

klein- bis großtropfige Leberzellverfettung

German to English Medical Medical (general)
Frischer, partiell hämorrhagischer Infarkt der Leber neben teils konfluierenden läppchenzentralen Nekrosen und einer **klein- bis großtropfigen Leberzellverfettung** von 30% der Hepatozyten.
Proposed translations (English)
4 +1 small to large fat globules/vesicles
2 small-to-large granular chirrosis

Discussion

Zareh Darakjian Ph.D. Sep 8, 2007:
Sorry:

The results of the current study demonstrated that the presence of fat in the liver of islet transplant recipients is a common finding on hepatic imaging and can be confirmed histologically. The fat infiltration on imaging, which was not present before transplantation, had either a focal or diffuse, though not homogeneous, pattern of hepatic involvement. Diffuse fatty infiltration of the liver with heterogeneous granular appearance on ultrasound is not a common finding in the general population.
Zareh Darakjian Ph.D. Sep 8, 2007:
Then: ** fatty liver with finely-to-coarsely granular appearance **
You may consider the following description (from he web)

The results of the current study demonstrated that the presence of fat in the liver of islet transplant recipients is a common
Bjørn Anthun Sep 8, 2007:
It's fatty liver disease (which can progress to cirrhosis) but the text doesn't state cirrhosis, so I'd stay with 'fatty liver'. My main problem is the part that says 'klein- bis großtropfige'.
Zareh Darakjian Ph.D. Sep 8, 2007:
Renate: Here they use *finely granular* so may be fine-to-coarse granular cirrhosis... is better..

Chronic veno-occlusive disease, a diffuse, finely granular cirrhosis.

Proposed translations

+1
4 hrs
Selected

small to large fat globules/vesicles

describing the interior of the hepatocytes

micro- and macrovesicular steatosis

Fatty disorders of the liver are defined by 2 major histologic patterns of steatosis within hepatocytes. Microvesicular steatosis is characterized by the presence of numerous small vesicles of fat that do not displace the nucleus (Figures 1, 2). Macrovesicular steatosis is characterized by engorgement of the hepatocyte by a large fat globule that displaces the nucleus.

http://www.medscape.com/viewarticle/449315
Peer comment(s):
agree Gisela Greenlee : globules would be my choice also for "Tropfen"
5 hrs
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Perfect! Thanks so much. I also found this: Histologisch unterscheidet man die großtropfige (makrovesikuläre) und die kleintropfige (mikrovesikuläre) Leberzellverfettung sowie Übergangsformen. http://de.wikipedia.org/wiki/Fettleber"
10 mins

small-to-large granular chirrosis

granular chirrosis exists, yet I am not so sure...

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Note added at 11 mins (2007-09-08 04:16:00 GMT)
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Sorry: ** cirrhosis **

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Note added at 20 mins (2007-09-08 04:25:25 GMT)
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So may be: ** finely-to-coarsely granular cirrhosis **

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Note added at 55 mins (2007-09-08 05:00:26 GMT)
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Fatty liver with finely-to-coarsely granular appearance...

Something went wrong...
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