English to Chinese Medical Chemistry; Chem Sci/Eng

Step 3. A mixture of 5-acetyl-indole-1-carboxylic acid tert-butyl ester [4.85g, 18.70 mmol, Intermediate (18)], ethylene glycol (5.0 g), pyridinium p-toluenesulfonate (100 mg) in benzene (35 mL) is refluxed under N2 with a Dean-Stark trap for 24 hours.
步骤3. 5 -乙酰-吲哚-1-羧酸叔丁基酯[ 4.85g, 18.70 mmol,中间体( 18)],乙二醇( 5.0 g),吡啶对甲苯磺酸吡啶嗡盐( 100 mg) 的苯溶液( 35 mL)在氮封条件下用Dean - Stark分水蒸馏接受管分镏24小时。