Glossary entry (derived from question below)
Greek term or phrase:
λεμφοαφανιστικός
English translation:
lymphodepleting
Greek term
λεμφοαφανιστικός
It's a conditioning regimen, but what is the "λεμφοαφανιστικό" part. I kind of understand it, but I can't find the equivalent English term.
I suspect I could leave it out without causing any real damage, but I prefer not to do that.
Can anybody help?
4 +2 | lymphodepleting | Haralabos Papatheodorou |
4 +1 | lymphoablative | Katerina Athanasaki |
3 +1 | lymphoablative | Ioanna Zampakidi |
3 | lymphodepletion | Mihailolja |
Proposed translations
lymphodepleting
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Note added at 11 mins (2021-11-17 09:14:25 GMT)
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The patients received a highly lymphodepleting conditioning regimen consisting of cyclophosphamide (60 mg/kg for 2 days) and fludarabine (25 mg/m2 for 5 days) before adoptive transfer of TILs. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1773008/)
Addition of Fludarabine to Cyclophosphamide Lymphodepletion Improves In Vivo Expansion of CD19 Chimeric Antigen Receptor-Modified T Cells and Clinical Outcome in Adults with B Cell Acute Lymphoblastic Leukemia
Administer a lymphodepleting regimen of cyclophosphamide and fludarabine before infusion of YESCARTA.
lymphoablative
https://www.frontiersin.org/articles/10.3389/fped.2019.00434...
Completely Non-Myeloablative/Non-Lymphoablative Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins
lymphodepletion
https://www.google.com/search?client=firefox-b-d&q=fludarabine+cyclophosphamide+lymphodepletion
lymphoablative
Using β-chain sequencing, we studied CD4 T cell diversity in 2 adult patients undergoing lymphoablative conditioning with cyclophosphamide (Cy), total body irradiation (TBI), and antithymocyte globulin (ATG) and autologous transplantation of hematopoietic cells depleted of T cells by enrichment for CD34 cells
https://www.infona.pl/resource/bwmeta1.element.elsevier-4937...
Nonmyeloablative stem cell transplantation using lymphoablative rather than myeloablative conditioning in the prefludarabine era by ATG and limiting doses of cyclophosphamide
https://pubmed.ncbi.nlm.nih.gov/15806133/
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