Glossary entry (derived from question below)
English term or phrase:
seeder-pig-challenge infection
Spanish translation:
contacto (de animales sanos) con cerdos previamente infectados
Added to glossary by
Brenda Joseph
May 2, 2018 18:28
6 yrs ago
8 viewers *
English term
seeder-pig-challenge infection
English to Spanish
Medical
Medical: Pharmaceuticals
Dose determination/justification
Three GCP compliant studies were performed to provide data on dose determination.
In the first study, respiratory disease was induced in 8 weeks old pigs by seeder-pig-challenge infection using A. pleuropneumoniae (MIC=2 µg/ml).
Pigs were treated with a single dose of saline or gamithromycin at 3, 4.5 or 6 mg/kg (n=20 pigs per group) by intramuscular (IM) injection. Animals were observed daily up to 7 days.
Three GCP compliant studies were performed to provide data on dose determination.
In the first study, respiratory disease was induced in 8 weeks old pigs by seeder-pig-challenge infection using A. pleuropneumoniae (MIC=2 µg/ml).
Pigs were treated with a single dose of saline or gamithromycin at 3, 4.5 or 6 mg/kg (n=20 pigs per group) by intramuscular (IM) injection. Animals were observed daily up to 7 days.
Proposed translations
(Spanish)
3 | contacto (de animales sanos) con cerdos previamente infectados |
Chema Nieto Castañón
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4 | infección por cerdo infeccioso introducido |
David Balayla
![]() |
Proposed translations
1 hr
Selected
contacto (de animales sanos) con cerdos previamente infectados
Desconozco si existe denominación específica en castellano y no he conseguido encontrar referencias en búsqueda rápida pero se refiere a contacto (de animales sanos) con cerdos previamente infectados.
Pej.
Characterization of an Actinobacillus pleuropneumoniae seeder pig challenge-exposure model (...)
Using each bacterial strain, infected pigs (termed seeder pigs) were commingled for 48 hours with 5 groups of noninfected test pigs, then were removed. Seeder and test pigs were maintained in isolation and were observed for 14 days
https://www.ncbi.nlm.nih.gov/m/pubmed/7887514/
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Note added at 1 hr (2018-05-02 20:15:44 GMT)
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Perdón; qué malas son las prisas. En este caso parece aludirse a los cerdos infectados por inoculación, sin referencia a los animales control utilizados como referencia en el estudio previamente referenciado;
respiratory disease was induced in 8 weeks old pigs by seeder-pig-challenge infection using A. pleuropneumoniae
enfermedad respiratoria fue inducida en cerdos de 8 semanas de edad mediante inoculación (infección inducida) [¿de cerdos a los que posteriormente se expondrán animales sanos?] utilizando A. pleuropneumoniae
Pej.
Characterization of an Actinobacillus pleuropneumoniae seeder pig challenge-exposure model (...)
Using each bacterial strain, infected pigs (termed seeder pigs) were commingled for 48 hours with 5 groups of noninfected test pigs, then were removed. Seeder and test pigs were maintained in isolation and were observed for 14 days
https://www.ncbi.nlm.nih.gov/m/pubmed/7887514/
--------------------------------------------------
Note added at 1 hr (2018-05-02 20:15:44 GMT)
--------------------------------------------------
Perdón; qué malas son las prisas. En este caso parece aludirse a los cerdos infectados por inoculación, sin referencia a los animales control utilizados como referencia en el estudio previamente referenciado;
respiratory disease was induced in 8 weeks old pigs by seeder-pig-challenge infection using A. pleuropneumoniae
enfermedad respiratoria fue inducida en cerdos de 8 semanas de edad mediante inoculación (infección inducida) [¿de cerdos a los que posteriormente se expondrán animales sanos?] utilizando A. pleuropneumoniae
4 KudoZ points awarded for this answer.
Comment: "Gracias!"
1 day 1 hr
infección por cerdo infeccioso introducido
En el primer estudio se indujo (la) enfermedad respiratoria en cerdos de 8 semanas mediante la infección por ***cerdo infeccioso introducido*** utilizando A. pleuropneumoniae.
Utilizaría 'introducido' como aproximación a la traducción de 'challenge'. 'Seeder' es el animal infectado e infeccioso que se introduce en la población sana o no infectada.
Utilizaría 'introducido' como aproximación a la traducción de 'challenge'. 'Seeder' es el animal infectado e infeccioso que se introduce en la población sana o no infectada.
Reference:
https://www.3tres3.com/articulos/protocolos-de-salud-para-la-entrada-de-reemplazos-1-3_36364/
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