Symptomatic restless legs syndrome may occur secondary to iron deficiency, anemia, folate deficiency, uremia, thyroid problems, diabetes, or peripheral neuropathy. (WE MOVE )

Restless legs syndrome may be triggered by peripheral neuropathy or radiculopathy, but a distinction should be made between these disorders. In pure peripheral neuropathy and radiculopathy, patients do not have the compelling need to move to relieve leg discomfort and the symptoms are not consistently worse at rest or at night. (EMIS & PiP)

Restless legs syndrome can begin at any age and generally worsens as you get older. Women are more likely than men to develop this condition. Restless legs syndrome can disrupt sleep — leading to daytime drowsiness — and make travelling difficult. (Mayo Foundation for Medical Education )