English to Spanish Medical Medical (general)

En un estudio clínico sobre seguridad y eficacia de un Inhibidor del cotransportador sodio-glucosa tipo 2 (SGLT2) en el tratamiento de pacientes con diabetes mellitus de tipo 2:

"There are 6 subtypes of sodium glucose co-transporter (SGLT), and mainly SGLT1 and SGLT2 are known to be involved in glucose reabsorption in the kidneys. SGLT2 is predominantly located on the **early segment of the proximal renal tubule** (S1 and S2 segments), has a low affinity, and is responsible for reabsorption in blood of most glucose which has been filtered in the glomeruli from the blood and transferred into glomerular filtrate. By contrast, SGLT1 is located in the late segment of the proximal renal tubule (S3 segment) where the glucose concentration is low, has a high affinity for glucose, and is involved in the almost complete reabsorption of glucose into the blood from glomerular filtrate. "

proximal renal tubule = túbulo renal proximal

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